Department
Sciences & Mathematics
Format of Presentation
Poster
Research Category
STEM
Description
Cancer is a widely dreaded disease that has an impact on millions of people worldwide. Among the various factors contributing to its development, one bacterium has gained some attention - Helicobacter pylori. It is the only bacterium that is identified as a carcinogen, which grows the concerns surrounding its presence in the human body. This study focuses on two distinct strains of H. pylori: H. pylori J99, known for carrying the CagA protein, and H. pylori A45, lacking this protein. We are looking at the cagA gene specifically because it is known to make the strain more likely to cause cancer. By comparing these strains, I aim to propose a hypothesis to explore if moving the cagA gene into the H. pylori A45 strain and observing if it causes more cancer.
Recommended Citation
Bagwell, Madison, "Exploring the Effect of CagA: A Comparative Study of Helicobacter pylori Strains J99 and A45 " (2024). Undergraduate Research Conference. 2.
https://athenacommons.muw.edu/urc/2024/posters-i/2
Exploring the Effect of CagA: A Comparative Study of Helicobacter pylori Strains J99 and A45
Cancer is a widely dreaded disease that has an impact on millions of people worldwide. Among the various factors contributing to its development, one bacterium has gained some attention - Helicobacter pylori. It is the only bacterium that is identified as a carcinogen, which grows the concerns surrounding its presence in the human body. This study focuses on two distinct strains of H. pylori: H. pylori J99, known for carrying the CagA protein, and H. pylori A45, lacking this protein. We are looking at the cagA gene specifically because it is known to make the strain more likely to cause cancer. By comparing these strains, I aim to propose a hypothesis to explore if moving the cagA gene into the H. pylori A45 strain and observing if it causes more cancer.